Mesoporous Silica Nanoparticles (MSN): A Nanonetwork and Hierarchical Structure in Drug Delivery
نویسنده
چکیده
According to IUPAC nomenclature, mesoporous materials are those materials having a pore size ranging from 2 to 50nm in diameter [1-6]. Mesoporous silica nanoparticles (MSNs) are promising and novel drug vehicles due to their unique mesoporous structure, which preserve a level of chemical stability, surface functionality and biocompatibility and ensure controlled release and targeted delivery of a variety of drug molecules. MSNs were discovered in 1992 by the Mobile Oil Corporation. They have received considerable attention due to their outstanding features, such as a high surface area, large pore volume, tunable pore diameter, narrow pore size distribution [7-15], easily modified surface [16], good biocompatibility and thermal stability [17].
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